You can change the roster when Paddack returns. Use the 60 day injured list to add depth now knowing they will need it later.
There is an obsession about the 26 man opening day roster when we should all realize the Twins will need the entire 40 man roster plus 10-20 other players to make it through the season. If they can add depth now they should. A pitcher they add now doesn't even have to be better than Emilio Pagan, he has to be better (at the start of the season) than the minor league free agents they have signed and the prospects that will begin the season in the minors. Any healthy pitcher who can put up a 4.50 ERA will be better than what they can get from Paddack in April. Find someone who lets them option Trevor Megill (and his lousy 81 ERA+ out of the bullpen) to AAA for a month.
David Price was good last year. Chad Kuhl could be a good candidate for a relief conversion. Michael Fulmer, Brad Hand, Archie Bradley, Hunter Strickland. Watch the waiver wire.